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Case Studies


TRACK-TBI sites throughout the United States will enroll 3,000 patients across the spectrum of mild to severe brain injuries. Clinical, imaging, proteomic, genomic and clinical outcome databases will be linked into a shared platform that will promote a model for collaboration among scientists within InTBIR and elsewhere.


CENTER-TBI is a large European project that aims to improve the care for patients with Traumatic Brain Injury (TBI). It forms part of the larger global initiative InTBIR: International Initiative for Traumatic Brain Injury Research whose goal is to bring together many of the world’s leading TBI experts and the latest technologies in an effort to tackle the silent epidemic of TBI. This research initiative includes over 100 hospitals across Europe, China, India, and Australia.

Hennepin County Medical Center

QuesGen Systems is the data management platform selected to work with Hennepin County Medical Center (HCMC) on the nation’s largest, single-center prospective study on concussion and TBI. The study is being led by HCMC’s neurosurgeon
Dr. Uzma Samadani to develop objective, multi-modal classication schemes and outcome measures for traumatic brain injury (TBI).

Client Testimonials

“The QuesGen database platform has been integral to allowing us to quickly and easily access data on our cohort of patients. Our goal in establishing the database was to better understand our patient population and to be able to have the ability for comparative analyses with like institutions. The ease of the platform and the support provided were added elements that have proven essential to its utility.” Odette Harris, MD, MPH Stanford

“One Mind has provided significant support to QuesGen in the development of the electronic data capture platform for deployment of the TRACK-TBI, CENTER-TBI and other TBI studies. The team at QuesGen understands the objectives of One Mind and is building tools that will enable investigators to share data and embrace the “Open Science” paradigm. We look forward to continuing our relationship with QuesGen for years to come”.

General Peter Chiarelli, OneMind

“We’ve been using the QuesGen System for the past seven years or so with great success. The system is very user friendly.  It’s built on the front-end with users in mind, and the back-end analysis incorporates the research staff. We originally considered using REDCap (a free internal tool) instead, but quickly realized that it would not allow for the analysis that we needed. Even though our technical expertise is limited, the QuesGen platform has increased the productivity and accuracy of our case managers. And we’ve found the QuesGen team to be very responsive to our needs, they actually care about how they are helping us” Rochelle Dicker, M.D, UCSF – Director, San Francisco Wraparound Project

“It has always been a partnership with the QuesGen team. They always go above and beyond to work to help you accomplish your goals.” Geoffrey T. Manley MD, UCSF, San Francisco General Hospital – Track-TBI

F.A.Q. (Frequently Asked Questions)

Is our data secure?
We use all industry standard methods to ensure that your data is secure.  All data communication between your browser and our secure servers happens through a Secure Socket Layer (SSL) connection and is encrypted.  Our servers are located in a SAS-70 compliant data center behind a dedicated firewall.  All of the members of our team are experts in managing secure HIPAA data.
What do I need to run the system?
All access happens through a browser.  There are no servers or special hardware requirements.  All you need is a PC with a reasonably current browser.
How long does it take to get a study set up?
It depends on how much work that we have to do.  Typical projects are setup in one to two weeks, but larger, more complex systems can take longer.
How much does it cost?
The QuesGen platform is delivered using the Software as a Service (SaaS) model.  That means that you pay for the software only as you use it, rather than a large up-front purchase.  There is a per-user, per-month charge, as a setup fee which will cover the time required to configure your site by our team.  For more information about your specific situation, please contact us.
What types of studies can be done?
The platform has been designed to handle large, complex, multi-center studies.  Of course, we have many projects that are much simpler in nature.  Most of our projects are unique.  For example, we have done work in hematology, pediatric stroke, and peripheral arterial disease.  We have a number of clients in Traumatic Brain Injury (TBI) and pediatric obesity.  For both of those, we have a large number of pre-developed forms and data structures.
I don't know much about data management, do I need to get an expert on board before getting started?
No, we can work with your team and provide direction for the optimal data model for ease of data entry and analysis.  Typically, our clients will rely on statisticians to do the data analysis.  We can provide that assistance as well if required.
What if there is a disaster? What will happen to our data?
Our data is backed up securely every night and an encrypted copy is sent to a remote server. Should there ever be a problem that would take out the entire data center, a remote copy could be available quickly.
We have an existing database that we are using today. Can we migrate the data into the QuesGen System?
Yes, we can load the data if you can provide it to us in a standard format.  We also have tools that can load data directly from Microsoft Access databases.
My IT department gave me a bunch of security requirements that I don't understand. Can you work with them to address them?
Yes, we have been through that process many times.  We have detailed documentation that we can provide and can also work with your IT Security staff to address any questions or concerns that they have.
I can see how the forms work for getting data in, but how do I get it out for analysis?
We provide extract tools that allow you to select the data elements that you want to include, provide an ability to define the criteria and allow you to download the file in a standard format that can be easily loaded into any stats package or excel.
There are members of our team who have different roles (like data entry and data analysis, for example). It is ok for some to see PHI but not others. How can we handle that?
Each user can have a unique permission profile.  It can either be assigned individually or by group (e.g Data Analyst, Research Assistant, Site Administrator).  Each user has  PHI (Protected Health Information) indicator which will prevent or allow access to PHI.
Like the previous question, we would like to be able to allow different sites to enter data, but only have access to the data that they entered. We would like for the study coordinator to see all of the data. Can that be done?
Users can also be configured so that they have access only to data associated with a specific category (e.g. Site).  Other users can be configured to have access to all levels of data.
Some of our people have Macs. Do they work?
Any PC or Mac will work fine.  We work with current versions of all of the major browsers, including Firefox, Safari, Chrome, and IE.

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Burlingame, CA

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QuesGen, located in The San Francisco Bay Area